Study: Nearly one in five parents of food-allergic children are bullied

New research shows that food allergy bullying is not just a problem for food-allergic kids but also their parents too.

“We know children are often bullied about their food allergies,” says Dannielle Brown, MHS, lead author of the study. “What we weren’t aware of was how many parents are bullied by multiple sources. Of the 252 parents or guardians we surveyed, more than 17% said they had been bullied.”

Parents of children 4-17 years (school-age children) in the survey found it was helpful to take action to stop the bullying. 13% of parents/guardians spoke with their child, 7% spoke with the offender or the offender’s parent, 17% spoke with a teacher and 15% spoke with a principal or administrator. Almost 50% of those who did something to stop food allergy bullying said it was helpful.

Another important finding in the survey was that while there were no significant differences in the percentages of Black and white children who were bullied around food allergies.

“No child or their parent should be bullied because of their food allergies,” says food allergy researcher Ruchi Gupta, MD, MPH, ACAAI member and one of the lead researchers on the study. “Having a food allergy puts tremendous stress on the entire family and any form of bullying makes life that much harder.”

Study finds antibiotics before age 2 associated with childhood health issues

In a retrospective case study, Mayo Clinic researchers have found that antibiotics administered to children younger than 2 are associated with several ongoing illnesses or conditions, ranging from allergies to obesity. The findings appear in Mayo Clinic Proceedings.

Using health record data from the Rochester Epidemiology Project, a population-based research collaboration in Minnesota and Wisconsin, researchers analyzed data from over 14,500 children. About 70% of the children had received at least one treatment with antibiotics for illness before age 2. Children receiving multiple antibiotic treatments were more likely to have multiple illnesses or conditions later in childhood.

Types and frequency of illness varied depending on age, type of medication, dose and number of doses. There also were some differences between boys and girls. Conditions associated with early use of antibiotics included asthma, allergic rhinitis, weight issues and obesity, food allergies, attention deficit hyperactivity disorder, celiac disease, and atopic dermatitis. The authors speculate that even though antibiotics may only transiently affect the microbiome, the collection of microbes in the body, this may have long-term health consequences.

“We want to emphasize that this study shows association ,not causation of these conditions,” says Nathan LeBrasseur, Ph.D., a researcher at Mayo Clinic’s Robert and Arlene Kogod Center on Aging and the study’s senior author. “These findings offer the opportunity to target future research to determine more reliable and safer approaches to timing, dosing and types of antibiotics for children in this age group.”

While recent data show an increase in some of the childhood conditions involved in the study, experts are not sure why. Other than the issue of multidrug resistance, antibiotics have been presumed safe by most pediatricians.

Researchers also say the ultimate goal is to provide practical guidelines for physicians on the safest way to use antibiotics early in life.

The Teal Pumpkin Project Continues This Halloween

Although Halloween looks different this year due to the COVID-19 Pandemic, The Teal Pumpkin Project continues in 2020. The Teal Pumpkin Project initiative aims to raise awareness surrounding food allergies by making Halloween safer and more inclusive for all trick-or-treaters while remaining mindful of the challenges presented by the ongoing COVID-19 pandemic.

“As families determine how to safely celebrate Halloween this year, FARE is reminding parents to make these celebrations as inclusive as possible for all children, including those with food allergies,” said Lisa Gable, chief executive officer of FARE.

The Teal Pumpkin Project encourages participants to place a teal pumpkin in front of their homes to show they have non-food treats available for children with food allergies or necessary dietary restrictions. Many popular Halloween candies contain nuts, milk, egg, soy, wheat or sesame, which are among the most common allergens. Additionally, many miniature candy items do not have labels and may be formulated or manufactured differently than full-sized candies of the same brand, making it difficult to determine whether these items are safe.  To learn more about the Teal Pumpkin Project, visit www.tealpumpkinproject.org.

Study: Spike in new nut anaphylaxis in children at Halloween and Easter

A new study looking at the link between peanut and tree-nut anaphylaxis in children and holidays found spikes at Halloween and Easter. The study, published in CMAJ (Canadian Medical Association Journal) found that most were previously unknown allergies, calling for increased awareness http://www.cmaj.ca/lookup/doi/10.1503/cmaj.200034.

“Identifying certain times associated with an increased risk of anaphylaxis could help to raise community awareness, support and vigilance,” write Dr. Melanie Leung, 4th-year medical student at McGill University and Dr. Moshe Ben-Shoshan, McGill University Health Centre, Montreal, Quebec, with coauthors. “This information would identify the best timing for public awareness campaigns to prevent allergic reactions.”

Researchers compared anaphylaxis at Halloween, Easter, Christmas, Diwali, Chinese New Year and Eid al-Adha.

The study included 1390 patients visiting participating pediatric emergency departments between 2011 and 2020 in 4 Canadian provinces: Quebec, Ontario, Newfoundland and Labrador, and British Columbia. The median age of patients was 5.4 years and 62% were boys.

For peanut-triggered anaphylaxis, there was an 85% increase in daily average cases during Halloween and a 60% increase during Easter compared with the rest of the year. For anaphylaxis triggered by unknown nuts, there was a 70% increase during Halloween and Easter compared with the rest of the year. However, the researchers did not find an increase at Christmas, Diwali, Chinese New Year or Eid al-Adha.

“The difference in the anaphylaxis incidence among holidays may have been due to the social setting in which each holiday takes place,” write the authors. “At Halloween and Easter, children often receive candies and other treats from people who may be unaware of their allergies. The absence of such an association at Christmas may be because Christmas is a more intimate celebration among family members and close friends, who are more vigilant regarding allergen exposure.”

Canadian labelling may also be a factor, as individual packages of candies and snacks, which are exempt from labelling requirements listing ingredients, are popular at Halloween and Easter.

The authors suggest education and awareness may help reduce the risk of anaphylaxis.

“Our findings suggest that educational tools to increase vigilance regarding the presence of potential allergens is required among children with food allergies, their families and lay people interacting with children who have food allergies. Newer strategies targeting intervals associated with high anaphylaxis risk are required.”

Therapy Helps Children with Food Allergies Manage Severe Anxiety

Imagine a young girl with a peanut allergy, so stricken by fear of anaphylaxis that she no longer takes part in everyday activities many children take for granted. She’s stopped playing with her siblings, worried that residue from their peanut butter crackers may trigger an allergic reaction. She obsessively washes her hands to make sure there is no trace of peanut on them. She worries that every stomachache could mean she accidently ate something she was allergic to.

This story is becoming more familiar to families across the country. While most children with food allergies maintain a healthy level of caution, there is a small percentage whose anxiety is excessive and impairing. The hallmark of excessive anxiety is going to extreme, medically unnecessary lengths to avoid the allergen, such as no longer visiting extended family or refusing to eat any allergen-free food that isn’t familiar. While these coping mechanisms may relieve anxiety in the short term, they may ultimately cause more harm by negatively reinforcing the idea that the world is a dangerous place and that children are helpless to keep themselves safe.

Now, Children’s Hospital of Philadelphia (CHOP) has launched the Food Allergy Bravery (FAB) Clinic to help children with a phobia of anaphylaxis. This revolutionary clinic, housed within the Food Allergy Center, is the first in the world to bring together psychologists and food allergy experts to treat food allergic children with severe phobia of anaphylaxis.

The three Founders of the FAB Clinic published a set of best practices in the Journal of Allergy and Clinical Immunology, providing guidance to allergists and pediatricians on how to address allergy-related phobias through Cognitive Behavioral Therapy (CBT).

“CBT works by gradually encouraging anxious children to take part in ‘brave practices,’ like eating with the rest of their family, playing with siblings, and trying new foods that don’t contain allergens,” said Katherine Dahlsgaard, PhD, ABPP, Director of the FAB Clinic at CHOP. “As a child’s confidence grows, we gradually introduce them to more challenging brave practices. This could include sitting in the same room with the food they’re allergic to, or even touching the food and then washing their hands thoroughly. The aim is to help children realize, through safe, structured practices in the FAB Clinic, that the world is much safer than they think and that they are capable of keeping themselves safe within it.”

The FAB clinic enthusiastically employs the help of family members, coaching parents or caregivers to repeat brave practices at home.

“We want these children and their families to know they’re safe and capable,” said Dr. Dahlsgaard. “Our ultimate goal is to equip families with practical skills and confidence via focused treatment sessions, so that their child can safely navigate a world that can’t always be allergen-free.”

Two-thirds of pediatricians not following full guidelines on peanut allergy prevention, report finds

As many as two-thirds of pediatricians in America do not follow the newest guidelines about how to introduce peanuts to children for allergy prevention, according to a new report.

The report, published in the Journal of the American Medical Association (JAMA) found that 93% of pediatricians are aware of the new guidelines, which were released in 2017 by the National Institute of Allergy and Infectious Diseases.

But less than 30% of pediatricians are following the guidelines in full, according to the report.

The guidelines issued in 2017 call for assessment of peanut-allergy risk and introduction of peanut- containing foods in the diet of infants at 4-6 months of age, in efforts to prevent peanut allergy. This is a reversal from 20 years ago, when the American Academy of Pediatrics recommended that peanut should be avoided until the child is 3 years old.

The survey data included responses from 1,781 pediatricians found that common barriers to guideline implementation included lack of clinic time, conducting in-office supervised feeding of peanut-containing food, performing peanut allergy testing, concerns about newness of the guidelines, and parental fear of allergic reactions. 

Researchers discover critical new allergy pathway

Mouse study discovery points to potential new drug targets for treating asthma, hay fever, and other inflammatory disorders

JOHNS HOPKINS UNIVERSITY BLOOMBERG SCHOOL OF PUBLIC HEALTH

Researchers at Johns Hopkins Bloomberg School of Public Health have identified the sequence of molecular events by which tiny, tick-like creatures called house dust mites trigger asthma and allergic rhinitis.

The researchers, whose study was published online June 22 in Nature Immunology, found that allergy-triggering molecules from dust mites can interact with an immune protein called SAA1, which is better known as a sentinel against bacteria and other infectious agents. The researchers showed step-by-step how this interaction between mite-molecules and SAA1 triggers an allergic-type immune response in mice.

The findings reveal what may be a significant new pathway by which allergic and inflammatory disorders arise. They also suggest that blocking the pathway could potentially work as a preventive or treatment strategy against asthma and other allergic reactions.

“We think that the signaling interactions that occur immediately downstream of the mite-proteins’ activation of SAA1 may be good targets for future drugs,” says study senior author Marsha Wills-Karp, PhD, the Anna M. Baetjer Professor of Environmental Health and Chair of the Department of Environmental Health and Engineering at the Bloomberg School.

Asthma affects between 8 to 15 percent of people in the U.S., and is typically triggered by dust mites, tree and grass pollens, and other allergens. Researchers suspect that this inappropriate immune triggering happens when the immune system mistakes allergens–which are otherwise harmless–for pieces of bacteria or other infectious agents. However, the molecular mechanisms underlying this misidentification haven’t been well understood.

In their study, Wills-Karp and her colleagues zeroed in on SAA1, an immune protein that is found, among other places, in the fluid that lines the airways and other mucosal surfaces. A member of the evolutionarily ancient “innate immune system” of mammals, SAA1 is thought to have evolved as a sentinel or early-responder molecule that, for example, recognizes and helps clear away certain types of bacteria and other infectious agents.

The researchers found that exposure to dust-mite proteins causes an asthma-like sensitization of the airways of the control group mice. In contrast, exposure to dust-mite proteins hardly had any effect in mice in which SAA1 was neutralized by antibodies, or in mice whose genes for SAA1 were knocked out. Further experiments confirmed that SAA1, when it is present, directly binds certain dust-mite allergens called fatty-acid binding proteins, which have structural similarities with proteins found in some bacteria and parasites. This allergen-SAA1 interaction releases SAA1 into its active form, wherein it activates a receptor called FPR2 on airway-lining cells. The airway cells then produce and secrete large quantities of interleukin-33, a protein known for its ability to stimulate allergic-type immune responses.

Confirming the likely relevance to humans, the researchers found evidence of increased production of SAA1 and FPR2 in nasal airway-lining cells from patients with chronic sinusitis–which is often linked to dust-mite allergens–compared to healthy controls.

“We think that different allergens take different routes to the activation of interleukin-33 and related allergic responses, and this SAA1-FPR2 route seems to be one that is taken by some dust-mite allergens,” Wills-Karp says.

She and her colleagues now plan to investigate why some people develop allergic disorders in which this pathway is hyperactive, while most don’t. They also plan to explore the possibility of blocking this pathway, perhaps at the SAA1-FPR2 interaction, as a way of treating asthma and other allergic disorders.

The researchers suspect that the newly described SAA1-FPR2 allergic pathway may be relevant not only in asthma and hay fever-type disorders but also in atopic dermatitis (eczema) and food allergies–possibly even in chronic inflammatory disorders such as rheumatoid arthritis and atherosclerosis.

Perth Picturesque in Teal

For the third consecutive year, Perth’s stunning Trafalgar Bridge triggered teal for Food Allergy Awareness Month from Friday the 15th to Saturday the 16th of May, 2020.

A very special thanks to all those at Perth City Council for their commitment to making this happen once again, as well as to our good friend Dr. Anthony Chaffee (pictured), who last year took time to visit Trafalgar Bridge. This year, he and all health care workers all around the world are working tirelessly to help keep us all safe during the COVID-19 Pandemic. We thank you and salute you all for your efforts!

TURN IT TEAL was created by Cleveland, Ohio native Stephanie Lowe, who founded ‘Turn it Teal’ in 2014. The aim of which was to light as many prominent monuments and buildings as possible to highlight Food Allergy Awareness Month.
At TRIGGER Food Allergy Awareness we are proud to have helped to make the initiative global with the lighting of the Sydney Town Hall in 2017,
being the first building outside of North America to turn teal in support of Food Allergy Awareness and have since lit Brisbane, Melbourne, Perth and Tasmania.

For more information about this initiative please visit turnitteal.org or email us at info@triggerawareness.org – Thank you.

Teal Time in Brisbane!

As Food Allergy Awareness Month rolled on, Brisbane lit up its beautiful Story and Victoria Bridges in teal to support those with food allergies, and help raise awareness.

Despite COVID-19, the two bridges dazzled and lit a teal beacon for those with food allergies. A special thank you once again to the team at the Brisbane City Council, who made this effort possible!

Another thank you to GlobalAAI.org for your continued support!

TURN IT TEAL was created by Cleveland, Ohio native Stephanie Lowe, who founded ‘Turn it Teal’ in 2014. The aim of which was to light as many prominent monuments and buildings as possible to highlight Food Allergy Awareness Month.
At TRIGGER Food Allergy Awareness we are proud to have helped to make the initiative global with the lighting of the Sydney Town Hall in 2017,
being the first building outside of North America to turn teal in support of Food Allergy Awareness and have since lit Brisbane, Melbourne, Perth and Tasmania.

For more information about this initiative please visit turnitteal.org or email us at info@triggerawareness.org – Thank you.

Tasmania Triggers Teal in 2020

Australia is all set to raise Food Allergy Awareness throughout May and will ‘Turn It Teal’ to shine a light on food allergies, which affect millions around the world.

This year, despite the COVID-19 Pandemic, we welcomed aboard Launceston, Tasmania, who was the first city to switch on the teal lights for 2020 and illuminated the stunning Launceston Town Hall from May 1st to May 4th, 2020.

This was the inaugural year for Tasmania to join the initiative and we thank all at Launceston City Council who helped to make this happen.

TURN IT TEAL was created by Cleveland, Ohio native Stephanie Lowe, who founded ‘Turn it Teal’ in 2014. The aim of which was to light as many prominent monuments and buildings as possible to highlight Food Allergy Awareness Month.
At TRIGGER Food Allergy Awareness we are proud to have helped to make the initiative global with the lighting of the Sydney Town Hall in 2017,
being the first building outside of North America to turn teal in support of Food Allergy Awareness, and have since lit Brisbane, Melbourne, Perth and now Tasmania.

For more information about this initiative please visit turnitteal.org or email us at info@triggerawareness.org – Thank you.

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